Scientists produce mice with cells from two males in a major breakthrough

Web Desk 11:29 PM | 19 Mar, 2023
Scientists produce mice with cells from two males in a major breakthrough

Scientists have made a major breakthrough by producing a mice with two biological fathers.

The method, which was unveiled on March 8 at the Third International Conference on Human Genome Editing in London, is a preliminary demonstration of a method that suggests the means to address some causes of infertility or possibly allow for single-parent embryos. 

Transforming male XY sex chromosomes into female XX ones was the goal of the research, which is still in its early phases.

This accomplishment has been the focus of research for years. One group published a study in 2018, describing the production of pups with either two fathers or two moms utilising embryonic stem cells derived from sperm or eggs. Puppies with two mothers grew up and were fruitful while those with two fathers only had a short lifespan.

Keith Latham, a developmental biologist at Michigan State University in East Lansing, argues that this is a tremendous advancement with enormous potential applications.

Katsuhiko Hayashi, a pioneer in the field of lab-grown sperm and eggs, who oversaw the project at Kyushu University in Japan, said that this was the first instance of producing strong animal oocytes from male cells.

Researchers firstly created "induced pluripotent stem cells" from skin cells removed from the tails of male mice. These cells have the capacity to differentiate into a variety of different cell or tissue types. They then developed functioning egg cells by converting male mouse stem cells into female cells through a process that involved expanding them and administering a medication. The embryos were then placed into female mice after being fertilised. Seven out of 630 embryos, or around 1%, developed into living mouse pups.

Finally, the pups seemed to develop normally and were able to become parents in the typical manner.

However, the discovery opens up the possibility of a wide range of new reproductive options, including the possibility that same sex male couples or even a single man could conceive a biological child without the need for a female egg.

Web Desk
Web Desk

Daily Pakistan Global Web Desk


Today's currency exchange rates in Pakistan - Dollar, Euro, Pound, Riyal rates on June 5, 2023

KARACHI - Following are the foreign currency exchange rates for US Dollar, Saudi Riyal, UK Pound Sterling, U.A.E. Dirham, European Euro, and other foreign currencies in Pakistan open market on June 5, 2023 (Monday).

Source: Forex Association of Pakistan. (last update 09:00 AM)

Currency Symbol Buying Selling
US Dollar ‎USD 305 308
Euro EUR 322 325
UK Pound Sterling GBP 377 381
U.A.E Dirham AED 82 83
Saudi Riyal SAR 80 81.2
Australian Dollar AUD 202 204
Bahrain Dinar BHD 758.24 766.24
Canadian Dollar CAD 228 230
China Yuan CNY 40.18 40.58
Danish Krone DKK 41.16 41.56
Hong Kong Dollar HKD 36.39 36.74
Indian Rupee INR 3.45 3.56
Japanese Yen JPY 2 2.08
Kuwaiti Dinar KWD 927 936
Malaysian Ringgit MYR 61.94 62.54
New Zealand Dollar NZD 173.16 175.16
Norwegians Krone NOK 25.67 25.97
Omani Riyal OMR 740.5 748.5
Qatari Riyal ‎QAR 78.37 79.07
Singapore Dollar SGD 220 222
Swedish Korona SEK 26.36 26.66
Swiss Franc CHF 314.07 316.57
Thai Bhat THB 8.21 8.36

Today's gold rates in Pakistan | gold price in Pakistan – June 6, 2023

Gold Rate In Pakistan Today:

KARACHI – The price of a single tola of 24-karat gold in Pakistan is Rs 228,900 on Tuesday. The price of 10 grams of 24k gold was recorded at Rs197,190.   

Likewise, 10 grams of 22k gold were being traded for Rs180,756 while a single tola of 22-karat gold was being sold at Rs 210,832.

Note: The gold rate in Pakistan is fluctuating according to the international market so the price is never been fixed. The below rates are provided by local gold markets and Sarafa Markets of different cities.

Gold Price in Pakistan: Lahore, Karachi, Islamabad

City Gold Silver
Lahore PKR 228,900 PKR 2125
Karachi PKR 228,900 PKR 2125
Islamabad PKR 228,900 PKR 2125
Peshawar PKR 228,900 PKR 2125
Quetta PKR 228,900 PKR 2125
Sialkot PKR 228,900 PKR 2125
Attock PKR 228,900 PKR 2125
Gujranwala PKR 228,900 PKR 2125
Jehlum PKR 228,900 PKR 2125
Multan PKR 228,900 PKR 2125
Bahawalpur PKR 228,900 PKR 2125
Gujrat PKR 228,900 PKR 2125
Nawabshah PKR 228,900 PKR 2125
Chakwal PKR 228,900 PKR 2125
Hyderabad PKR 228,900 PKR 2125
Nowshehra PKR 228,900 PKR 2125
Sargodha PKR 228,900 PKR 2125
Faisalabad PKR 228,900 PKR 2125
Mirpur PKR 228,900 PKR 2125


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